Can You Take Copper with Polyunsaturated Fatty Acids?

Taking copper supplements with polyunsaturated fatty acids may lead to decreased levels of these essential fatty acids. This interaction could potentially impact heart health and inflammation. Copper's toxic effect on fatty acids may be a concern for individuals taking high doses of either supplement. Copper has been shown to have a toxic effect on fatty acids, particularly polyunsaturated fatty acids (PUFAs), leading to a decrease in their levels. This may be due to copper's ability to alter the composition of cell membrane phospholipids, which can affect fatty acid metabolism. Specifically, copper can increase the oxidation of PUFAs, making them more susceptible to degradation.