Can You Take Arachidonic Acid with NADH?
Arachidonic Acid May Interfere With NADH Effectiveness
Reduced NADH Effectiveness
Arachidonic Acid May Interfere With NADH Effectiveness
Reduced NADH Effectiveness
Detailed Analysis
Taking Arachidonic Acid and NADH together may reduce the effectiveness of NADH. Arachidonic Acid can inhibit a key enzyme that NADH relies on. This could impact energy production in the body. Arachidonic Acid acts as an uncompetitive inhibitor against NADH, specifically blocking the NADH-CoQ oxidoreductase enzyme. This means it binds to the enzyme and reduces its activity, making it harder for NADH to do its job. The Ki value for this interaction is 22 microM, indicating a moderate level of inhibition.
What else do you take?
2/10Check your full stack — every pair, not just this one
Optimal Timing
⏱️ NADH separated from Arachidonic Acid by 5.5h (Arachidonic acid acts as an uncompetitive inhibitor against NADH with a Ki value)
Research Sources (1)
This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any supplement regimen.