Can You Take Polyunsaturated Fatty Acids with Vitamin D?

Taking polyunsaturated fatty acids and vitamin D together may have additive and possibly synergistic effects on overall health. The combination may help decrease the intensity of free radical processes and improve absorption. This can lead to enhanced benefits for heart health and cancer prevention. The administration of ω-3 polyunsaturated fatty acids (PUFAs) and vitamin D3 has been shown to decrease the intensity of free radical processes. ω-3 PUFAs can decrease the apparent affinity of vitamin D metabolites for human vitamin D-binding protein, which may affect vitamin D's activity in the body. Free radical processes refer to unstable molecules that can cause cell damage, and decreased intensity means less damage.