Can You Take Phosphoserine with Vitamin B6?

Taking Phosphoserine and Vitamin B6 together does not seem to cause any significant issues. Research on their interaction is limited, but available evidence suggests no major concerns. You can likely take them together without worrying about adverse effects. No clear biochemical mechanism explains how Phosphoserine and Vitamin B6 interact. One study found that Phosphoserine can stimulate the excretion of pyridoxine, a form of Vitamin B6, in certain bacterial mutants, but this does not directly apply to human supplement use. A cofactor is a molecule that helps an enzyme work properly; in this case, no specific cofactor relationship is known.