Can You Take Melatonin with Tyrosine?

Research suggests that taking melatonin and tyrosine supplements together does not pose significant risks. Some studies indicate melatonin may affect tyrosine levels or activity, but this does not seem to cause harm. Overall, no major concerns have been raised about combining these two supplements. Melatonin may influence tyrosine levels or activity by potentially increasing tyrosine concentration or protecting against tyrosine nitration, a process where tyrosine is modified by a reactive nitrogen species. This could be relevant because tyrosine nitration can affect protein function.