Can You Take Kava with St John's Wort?
Kava and St John's Wort may cause liver damage when taken together
Liver damage risk
Kava and St John's Wort may cause liver damage when taken together
Liver damage risk
Detailed Analysis
Taking kava and St John's Wort at the same time may increase the risk of liver damage. A case study reported acute hepatitis in a healthy woman who took these supplements together. Liver biopsy showed significant damage. Kava and St John's Wort can induce cytochrome P450 enzymes, which are proteins that help break down medications in the liver. When these enzymes are overactive, they can decrease levels of certain medications and increase the risk of adverse effects. This may lead to liver damage.
What else do you take?
2/10Check your full stack — every pair, not just this one
Research Sources (2)
This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any supplement regimen.