Can You Take Epicatechin-3-Gallate with Epigallocatechin Gallate?

BENEFICIAL

Combining ECG and EGCG may enhance therapeutic effects under medical supervision.

7 studies

Strong evidence

Medical supervision recommended

BENEFICIAL

Combining ECG and EGCG may enhance therapeutic effects under medical supervision.

•

7 studies

•

Strong evidence

Medical supervision recommended

Detailed Analysis

✓ Complete

Taking Epicatechin-3-Gallate and Epigallocatechin Gallate together may modulate certain enzymes and inhibit specific proteins, potentially leading to enhanced therapeutic effects. This combination has been studied for its potential benefits in various health conditions. However, it is essential to use them under medical supervision. The combination of ECG and EGCG may modulate CYP isoforms, which are enzymes that play a crucial role in metabolizing drugs and other substances in the body. Additionally, this combination may inhibit matrix metalloproteinases (MMP-2/9) activity, which are proteins involved in the breakdown of tissue. This may contribute to the potential therapeutic benefits of using ECG and EGCG together.

What else do you take?

2/10

Check your full stack — every pair, not just this one

Epicatechin-3-GallateEpigallocatechin GallateAdd more

Optimal Timing

100%

Early Morning

6:00 – 7:30 AM

Epigallocatechin Gallate✨

Epicatechin-3-Gallate✨

✅ Epigallocatechin Gallate benefits from taking with Epicatechin-3-Gallate in the early morning

✅ Epicatechin-3-Gallate benefits from taking with Epigallocatechin Gallate in the early morning

Related Interactions

Glutathione + Epigallocatechin Gallate

Beneficial

3-Nitrotyrosine + Epigallocatechin Gallate

Beneficial

Epigallocatechin Gallate + Green Tea Extract

Beneficial

Research Sources (7)

Sex- and strain-dependent effects of epigallocatechin gallate (EGCG) and epicatechin gallate (ECG) in the mouse.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2006 · PMID: 16762473

Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549.

Toxicology in vitro : an international journal published in association with BIBRA · 2009 · PMID: 19406223

Bioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator.

PloS one · 2015 · PMID: 25747701

This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any supplement regimen.