Can You Take Creatine with Ornithine?
Creatine and Ornithine may harm each other when taken together
Reduced Creatine Effectiveness
Creatine and Ornithine may harm each other when taken together
Reduced Creatine Effectiveness
Detailed Analysis
Taking Creatine and Ornithine together may lead to reduced Creatine production and effectiveness. Ornithine can inhibit an enzyme crucial for Creatine synthesis. This interaction may cause muscle and eye problems. Ornithine inhibits the rate-limiting transamidination step, which is necessary for creatine production. This step involves the conversion of arginine and glycine into guanidinoacetate, a precursor to creatine. When ornithine blocks this step, less creatine is produced.
What else do you take?
2/10Check your full stack — every pair, not just this one
Research Sources (2)
This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any supplement regimen.