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Can You Take Citrulline with Proline?
MILD INTERACTION
Citrulline may slightly affect Proline uptake
3 studies
Limited evidence
Potential reduction in Proline uptake
MILD INTERACTION
Citrulline may slightly affect Proline uptake
•
3 studies
•
Limited evidence
Potential reduction in Proline uptake
Detailed Analysis
✓ Complete
When taken together, Citrulline may partially inhibit the uptake of Proline. This could potentially affect the efficacy of Proline. However, the impact is likely to be minor. L-citrulline partially inhibits a high-affinity transport system that helps L-proline enter cells. This transport system has a high capacity for L-proline. The inhibition may reduce L-proline uptake.
What else do you take?
2/10Check your full stack — every pair, not just this one
CitrullineProlineAdd more
Optimal Timing
100%
Early Morning
6:00 – 7:30 AM
Citrulline
Morning
8:00 – 10:00 AM
Proline
Research Sources (3)
Effects of heat shock on amino Acid metabolism of cowpea cells.
Plant physiology · 1990 · PMID: 16667781
Effect of Exogenous Proline on Metabolic Response of Tetragenococcus halophilus under Salt Stress.
Journal of microbiology and biotechnology · 2017 · PMID: 28683533
L-leucine transport systems in Saccharomyces cerevisiae participation of GAP1, S1 and S2 transport systems.
Cellular and molecular biology (Noisy-le-Grand, France) · 1994 · PMID: 7812191
This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any supplement regimen.