Can You Take Bromelains with Cysteine?

Research indicates that bromelains and cysteine do not have a significant interaction. Studies have shown that cysteine can induce V-type activation of bromelain under certain conditions, but this does not appear to have major implications for human supplement use. Overall, no special concerns are raised when taking these two supplements together. The biochemical mechanism between bromelains and cysteine is not well-defined. However, research suggests that cysteine may activate bromelain through a V-type activation, which refers to an increase in the enzyme's catalytic rate without affecting its substrate binding affinity. Nevertheless, no clear evidence suggests a significant mechanism of interaction that would impact human health.