Can You Take Arachidonic Acid with Diallyl Trisulfide?

Research suggests that combining Arachidonic Acid and Diallyl Trisulfide does not lead to any significant adverse interactions. A study found that Diallyl Trisulfide, a compound found in garlic oil, inhibits the arachidonic acid cascade at a specific reaction site, but this does not seem to cause any major issues. Overall, no special concerns are raised when taking these two supplements together. The biochemical mechanism involves Diallyl Trisulfide inhibiting the arachidonic acid cascade at the reaction site with PGH synthase, an enzyme that catalyzes two successive reactions in the production of prostaglandins. However, the study did not describe a significant interaction that would impact the safety or efficacy of Arachidonic Acid. PGH synthase is also known as cyclooxygenase or COX.