Can You Take Anserine with Creatine Monohydrate?

Taking Anserine and Creatine Monohydrate together does not seem to cause any significant interactions. Research on senescence-accelerated mice suggests that creatine supplementation can actually increase carnosine content in skeletal muscle, which is related to anserine. However, no direct interaction between anserine and creatine monohydrate has been identified. No mechanism of interaction was identified between anserine and creatine monohydrate. However, both compounds are involved in muscle function and antioxidant defenses. Creatine is known to affect muscle carnosine levels, which is a related histidine-containing dipeptide.