Can You Take Alpha-lipoic acid with Thiamine Hydrochloride?

Research shows that Alpha-lipoic acid and Thiamine Hydrochloride can form a complex in solution, but this doesn't seem to have significant effects on their stability or activity. In fact, low concentrations of Alpha-lipoic acid may even help stabilize Thiamine Hydrochloride solutions. Overall, no major concerns were raised about taking these supplements together. The exact biochemical mechanism is unclear, but it appears that Alpha-lipoic acid and Thiamine Hydrochloride can interact in a 1:1 complex. A complex is a type of molecular structure that forms when two or more molecules bind together. However, no specific biochemical effects of this interaction on human health were reported.